.
Articles on preprint server
(*same contribution, ^joint corresponding author, #corresponding author)
Mijajlovic, L., Hofacker, L. M., Lindner, F., Jayakumar, P., Diepold, A. & Huwiler, S. G.# Modulating gene expression and portein secretion in the bacterial predator Bdellovibrio bacteriovorus. bioRxiv https://doi.org/10.1101/2025.05.17.654431 (2025).
Lai, T. F., Jankov, D., Grossmann, J., Roschitzki, B. & Huwiler, S. G.# Quantitative proteome of bacterial periplasmic predation reveals a prey damaging protease. bioRxiv https://doi.org/10.1101/2024.12.23.6300892 (2024).
Mridha, S.^, Loose, S.-L.*, Mattmann, O. Ch.*, Isele, S., Kümmerli R. & Huwiler, S. G.^ Outer membrane changes enable evolutionary espcae from bacterial predation. bioRxiv https://doi.org/10.1101/2024.09.27.615459 (2024).
Peer-reviewed journals
(* joint first authorship, #corresponding author)
Tyson, J., Radford, P., Lambert, C., Till, R., Huwiler, S. G., Lovering, A. L. & Sockett, R. E. Prey killing without invasion by Bdellovibrio bacteriovorus defective for a MIDAS-family adhesin. Nat Commun. 15(1): 3078, doi: 10.1038/s41467-024-47412-32 (2024).
Lai, T. F., Ford, R. M. & Huwiler, S. G.# Advances in cellular and molecular predatory biology of Bdellovibrio bacterovorus six decades after discovery. Front Microbiol 14 : 1168709, doi: 10.3389/fmicb.2023.1168709 (2023).
Seelmann, C. S., Huwiler, S. G., Culka, M., Strampraad, M. J. F., Biskup, T., Weber, S., Ullmann, G. M., Schünemann, V., Hagedoorn, P.-L., Pierik, A. J. & Boll M. Enzymatic Birch reduction via hydrogen atom transfer at an aqua-tungsten-bis-metallopterin cofactor. ACS Catalysis 13: 8631-8641, doi: 10.1021/acscatal.3c01781 (2023).
Cavallaro, A., Rhoads, W.J., Huwiler, S. G., Stachler, E. & Hammes, F. Potential probiotic approaches to control Legionella in engineered aquatic ecosystems. FEMS Microbiol Ecol. June9; fiac071, doi: 10.1093/femsec/fiac071 (2022).
Harding, C. J.*, Huwiler, S. G.*, Somers, H., Lambert, C., Ray, L. J., Till, R., Taylor, G., Moynihan, P. J., Sockett, R. E. & Lovering, A. L. A lysozyme with altered substrate specificity facilitates prey cell exit by the periplasmic predator Bdellovibrio bacteriovorus. Nat Commun. 11(1): 4817, doi: 10.1038/s41467-020-18139-8 (2020).
Huwiler, S. G.*, Löffler C.*, Anselmann, S. E. L.*, Stärk, H. J., von Bergen, M., Flechsler, J., Rachel, R. & Boll, M. One-megadalton metalloenzyme complex in Geobacter metallireducens involved in benzene ring reduction beyond the biological redox window. Proc Natl Acad Sci U S A 116(6), 2259-2264, doi: 10.1073/pnas.1819636116 (2019).
Culka, M., Huwiler, S. G., Boll, M. & Ullmann, G. M. Breaking benzene aromaticity-computational insights into the mechanism of the tungsten-containing benzoyl-CoA reductase. J Am Chem Soc 139, 14488-14500, doi: 10.1021/jacs.7b07012 (2017).
Weinert, T.*, Huwiler, S. G.*, Kung, J. W., Weidenweber, S., Hellwig, P., Stärk, H. J., Biskup, T., Weber, S., Cotelesage J. J. H., George, G. N., Ermler, U. & Boll, M. Structural basis of enzymatic benzene ring reduction. Nat Chem Biol 11, 586-591, doi: 10.1038/nchembio.1849 (2015).
Eugster, M. R., Morax, L. S., Hüls, V. J., Huwiler, S. G., Leclercq, A., Lecuit, M. & Loessner, M. J. Bacteriophage predation promotes serovar diversification in Listeria monocytogenes. Mol Microbiol 97, 33-46, doi: 10.1111/mmi.13009 (2015).
Serventi, F., Youard, Z. A., Murset, V., Huwiler, S., Bühler, D., Richter, M., Luchsinger, R., Fischer, H. M., Brogioli, R., Niederer, M. & Hennecke, H. Copper starvation-inducible protein for cytochrome oxidase biogenesis in Bradyrhizobium japonicum. J Biol Chem 287, 38812-38823, doi: 10.1074/jbc.M112.406173 (2012).
Huwiler, S. G.#, Beyer, C., Fröhlich, J., Hennecke, H., Egli, T., Schürmann, D., Rehrauer, H. & Fischer, H. M. Genome-wide transcription analysis of Escherichia coli in response to extremely low-frequency magnetic fields. Bioelectromagnetics 33, 488-496, doi: 10.1002/bem.21709 (2012). #Corresponding author, based on setting up & managing own MSc thesis project including funding.